Guillaume was born in 1968 and, after engineering studies and directing two short film, he worked ten years for Canal+ in the cinema department and as an artistic producer for French public broadcaster France 2. Independent producer since 2000, he produced or co-produced more than 50 non-French feature arthouse films selected in every major festival and theatrically released in France.

The most recent films he co-produced under Arizona Productions are Yellow Cat by Adilkhan Yerzhanov, to be screened in the Orizzonti competition at the 2020 Venice film festival, and The Island Within by Ru Hasanov, to be screened at the 2020 Sarajevo film festival.